Vol. 4 No. 4 (2026)

Volume 4, Issue 4 features studies spanning cannabinoid pharmacology and nanotherapeutic engineering. A review examines the medical applications and misuse potential of cannabis, tracing the pharmacological mechanisms of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) through the endocannabinoid system, their therapeutic benefits for chronic pain, multiple sclerosis spasticity, chemotherapy-induced nausea, and epilepsy, and the emerging challenges of tolerance, withdrawal, and cannabis use disorder, particularly among adolescents. Another review investigates the engineering of nanotherapeutics to target mechanotransduction, cellular senescence, and regenerative signaling in wound healing, highlighting how liposomes, polymeric nanoparticles, and multifunctional nanostructures enable precise drug delivery while modulating growth factor signaling, immune responses, and tissue repair. Together, the articles reflect the journal's commitment to publishing diverse research from molecular pharmacology and neurotransmitter signaling to advanced nanomedical platforms with translational implications.